Triclops are non-aggressive creatures that only damage Samus if they make contact with her, or if they mistake her for rock or foodstuffs and draw her into their jaws for relocation. If she is caught, Samus will be carried and expelled into an area designated for either rock removal or food storage, and take damage. They can only be destroyed if Samus lays a Morph Ball Bomb in their path and a Triclops draws one in, mistaking it for either food or an obstruction.
In Metroid Prime 2: Echoes, Samus encounters Luminoth-made mechanoids designed to resemble Triclops, known as Mechlops. These were created after attempts to domesticate Triclops for use in war failed. This may indicate that the Luminoth transported specimens from Tallon IV for training, or found an indigenous group of Triclops elsewhere. Unused textual data indicates that Triclops and a Darkling variant called Dark Triclops were originally planned for use in Echoes.
- "Hard-shelled creature with powerful jaws.
The Triclops is a hunter-gatherer. It collects small creatures and bits of foodstuff, then deposits them elsewhere for later consumption. The hard tripartite mandibles it uses to move earth and rock are quite strong and difficult to escape once ensnared." — Logbook "Triclops" (Metroid Prime)
- "The Luminoth tried to domesticate and train a number of Triclops for use in war, but failed. Undaunted, they created mechanical versions of the hardy creatures to use in battle. The few Mechlops that remain now serve other mechanoids, turning their potent jaws and earthmoving power against their former masters." —Metroid Prime 2: Echoes Logbook "Mechlops" (Metroid Prime 2: Echoes)